The Sea Lane Influenza Antibodies are derived from our Comprehensive Influenza Library which is a compilation of human antibody repertoire libraries made from individual survivors of influenza infection. We chose bone marrow as the source material in constructing the library to access the full antibody repertoire of each individual.
Donors selected for the Comprehensive Influenza Library had exposure to H1N1, H2N2, H3N2 or H5N1 influenza sub-types and include survivors of the highly pathogenic H5N1 avian influenza infection. The Sea Lane Comprehensive Influenza Library is the the first ever collection of bone marrow-derived libraries to contain such individuals.
The Comprehensive Influenza Library is made up of ~ 10 billion members in Fab and scFv formats and has been used to identify antibodies that are broadly neutralizing across and within H5N1 (highly pathogenic avian influenza) and H1N1 (seasonal and 2009 pandemic influenza) sub-types and are currently being used to advance passive immunotherapy as a treatment option for influenza infection.
Click here for more information about our Influenza Antibodies.
Sea Lane is open to discuss business models that allow leverage into these resources.